Package: BIGDAWG 3.1.0

Steve Mack

BIGDAWG: Case-Cotrol Analysis of Multi-Allelic Loci

Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.

Authors:Derek Pappas [aut], Livia Tran [aut], Steve Mack [aut, cre], Jill Hollenbach [aut]

BIGDAWG_3.1.0.tar.gz
BIGDAWG_3.1.0.zip(r-4.7-any)BIGDAWG_3.1.0.zip(r-4.6-any)BIGDAWG_3.1.0.zip(r-4.5-any)
BIGDAWG_3.1.0.tgz(r-4.6-any)BIGDAWG_3.1.0.tgz(r-4.5-any)
BIGDAWG_3.1.0.tar.gz(r-4.7-any)BIGDAWG_3.1.0.tar.gz(r-4.6-any)
BIGDAWG_3.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
BIGDAWG/json (API)

# Install 'BIGDAWG' in R:
install.packages('BIGDAWG', repos = c('https://igdawg.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/igdawg/bigdawg/issues

On CRAN:

Conda:

5.92 score 4 stars 1 packages 4 scripts 596 downloads 7 mentions 77 exports 10 dependencies

Last updated from:7f006b2a27. Checks:3 WARNING, 2 OK, 4 FAIL. Indexed: yes.

TargetResultTimeFilesSyslog
linux-develWARNING169
source / vignettesOK213
linux-releaseWARNING167
macos-releaseFAIL89
macos-oldrelFAIL114
windows-develWARNING88
windows-releaseFAIL49
windows-oldrelFAIL63
wasm-releaseOK135

Exports:AA.wrapperAA.df.checkAA.df.csAAtable.builderAlignmentFilterAlignObj.CreateAlignObj.UpdateAppend.SystemBIGDAWGBuild.MatrixbuildHAPnamesbuildHAPsetsccicci.pvalcci.pval.listCheck.CoresCheck.DataCheck.ParamsCheck.Params.GLSCheckAllelesCheckHLACheckLociCheckReleaseCheckString.AlleleCheckString.LocusCondense.EPLCreate.Null.TableDRB345.Check.WrapperDRB345.Check.ZygosityDRB345.ExpDRB345.parserErr.LogEVSremovalExon.FilterExonPtnAlign.CreateExonPtnListFillerFormat.AlleleFormat.TabgetAllele.CountgetCS.MatgetCS.statGetFieldgetFileNameGetFilesgetHapgetObsFreqGL2Tab.LociGL2Tab.SubGL2Tab.wrapperGLSconvertH.MCH.MC.wrapperHLA_dataHWEHWE.ChiSqHWE.wrapperLL.wrappermake2x2makeCombMergeData_OutputPgrpExtractPgrpFormatPreCheckprepDatarmABstringsRunChiSqRunChiSq_cStrippersummaryGeno.2Tab2GL.LociTab2GL.SubTab2GL.wrapperTableMakerUpdateRelease

Dependencies:arsenalevaluategluehaplo.statshighrknitrMASSxfunXMLyaml

BIGDAWG
Overview | Input Data | Data Output | Error Messages and Codes | Known Issues | Parameters | Examples | Updating the bundled IMGT/HLA protein alignment | Updating BIGDAWG to latest developmental versions

Last update: 2026-04-30
Started: 2021-01-27

GLSconvert
Overview | Anatomy of a GL String | Input Data | Data Output | Parameters | Examples

Last update: 2022-10-18
Started: 2021-01-27